H2020-HCA Cluster Communication Group Newsletter
Welcome to the second edition of the H2020-HCA Cluster Communication Group's newsletter. The group consists of representatives from the six pilot actions (BRAINTIME, discovAIR, ESPACE, HCA|Organoid, HUGODECA, HUTER) that were funded under the Horizon 2020 call H2020-SC1-2019 to contribute to the Human Cell Atlas (HCA) initiative.
The HCA aims to create comprehensive reference maps of all human cells—the fundamental units of life—as a basis for both understanding human health and diagnosing, monitoring, and treating disease. Each of the pilot actions has been designed to characterize single cells or their nuclear components, their interactions and/or spatial location in tissues from one human organ.
In this newsletter, we have gathered a series of news articles and interviews, listed recent publications by the consortia, and collected information on relevant upcoming events to inform you about the progress of the cluster. We hope you enjoy the read.
Best wishes,
The H2020-HCA Cluster Communication Group
P.S. Please share this newsletter with your colleagues and networks.
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discovAIR launched the Human Lung Cell Atlas
On 11 March 2022, the official launch of the Human Lung Cell Atlas (HLCA) by the discovAIR consortium took place during the ERS Lung Science Conference in Estoril, Portugal. Malte Lücken (Helmholtz Center Munich) introduced the HLCA during his presentation and showed the potential of the atlas. During the breaks and poster sessions interested people tried out the HLCA offered as an open-access dataset on the FASTGenomics platform of the discovAIR partner Comma Soft. Read more »
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ESPACE: Interview with Anna Martinez Casals, Researcher at SciLifeLab
The ESPACE communications team recently met with Dr Martinez Casals, Researcher at SciLifeLab in Stockholm, Sweden, to learn more about her work in ESPACE's Work Package 4, the innovative cell segmentation techniques used by her and her team, and what motivates her in her career. Read more »
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HCA|Organoid: Interview with Sabrina Ladstätter, Scientific Project Manager at CeMM
As scientific project manager of the HCA|Organoid project, Sabrina Ladstätter works closely together with all partners of the consortium to build an “Organoid Cell Atlas” based on massive-scale single-cell profiling of human organoids. Find out more about her work in this interview, and why she's particularly fascinated by the little things that can often make a big difference. Read more »
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Dr. Garrido and Dr. Mas to present at SRI their latest developments within HUTER
Dr. Garrido & PhD student Irene Muñoz and team with the abstract titled “Single-cell atlas of defective decidualization in preeclampsia reveals different endometrial cell composition”, was selected for an oral presentation in a concurrent oral session at the Society for Reproductive Investigation’s 69th Annual Scientific Meeting as well as her colleague Dr. Mas abstract titled “Single Cell Transcriptomic Atlas Characterization of the Myometrium in Menopausal Women”, selected for a poster presentation. The talk took place at the preeclampsia session on March 18th 2022 and the poster was presented at the Reproductive Biology session on March 17th 2022, Denver, EEUU. Read more »
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discovAIR: Information about discovAIR project on the European Lung Foundation website
The patient-led organisation European Lung Foundation created a page to present information and result updates of the discovAIR project to the general public. The page contains a 3D animation to explain the project, an overview and in-depth project approach. Updates about the project results will be posted in the future. Read more »
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The ESPACE Cloud – A snapshot
The ESPACE Cloud was developed in the context of ESPACE's Work Package 5, ‘Data Management – DCP Pancreas’, by a team from the Center of Digital Health at the Charité. In this article, Dr. Sven Twardziok shares insights into the cloud design process. Read more »
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HUTER launches its YouTube channel
Four interviews to the research team can be watched on the new project's YouTube channel where you will learn more about their work and latest developments of the project. The researchers interviewed are from INCLIVA (Spain) and the University of East Anglia (United Kingdom). We will continue updating the channel with new content. We invite you to subscribe! Read more »
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discovAIR: HLCA workshop
To explain the Human Lung Cell Atlas in more detail and to highlight the possibilities for the community, discovAIR will soon offer a short workshop. If you are interested in attending the event, please add your contacts to this pre-registration form. DiscovAIR will get in contact with you when the date and details of the workshop are decided.
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ESPACE: Industry-Academia Webinar
May 31, 2022 | 14:00-17:45 CEST
ESPACE is hosting a webinar titled "Building a Human Cell Atlas of the Pancreas". The webinar consists of two parts: an introduction of state-of-the-art single-cell technologies by industry partners as well as presentations of ESPACE findings by members of the consortium to demonstrate the project's achievements towards building a human cell atlas. You can now register here »
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HUTER: Training session “cloud-based open access platform, validation of its usability”
June 23, 2022 | 14:45-16:15h CEST | Valencia, Spain
Following the Final HUTER Steering Committee, attendes and general public will received a training session on the applications and how to use the platform developed within the HUTER project. A webinar session will be opened for those researchers interested in learning more in depth. For more information please contact eflores@incliva.es.
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11th Conference of the Research and Innovation Framework Program of the European Union
April 6, 2022 | 14:45-16:15h CEST | Valencia, Spain
More information »
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Human Cell Atlas: HCA Biological Network Seminar Series featuring the Reproduction Network
April 14, 2022 | Online
More information »
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Human Cell Atlas: HCA Biological Network Seminar Series featuring the Immune Network
May 12, 2022 | Online
More information »
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Human Cell Atlas: HCA Biological Network Seminar Series featuring the Kidney Network
June 9, 2022 | Online
More information »
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Human Cell Atlas: HCA General Meeting
June 27-29, 2022 | Online and Vienna, Austria (hybrid)
For more information, please contact: hca@humancellatlas.org.
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Human Cell Atlas: HCA Developmental and Pediatric Cell Atlas 2022 Meeting
November 20-22, 2022 | Online and Paris, France (hybrid)
For more information, please contact: hca@humancellatlas.org.
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Recent Publications
- Hollandi, R, Moshkov, N, Paavolainen, L, et al. (2022) Nucleus segmentation: towards automated solutions. Trends in Cell Biology, Vol. 32, Issue 4,pp 295-310; doi: https://doi.org/10.1016/j.tcb.2021.12.004.
- Lotfollahi, M, Naghipourfar, M, Luecken, MD, et al. (2022) Mapping single-cell data to reference atlases by transfer learning. Nat Biotechnol 40, 121–130; doi: https://doi.org/10.1038/s41587-021-01001-7
- Luecken, MD, Zaragosi, LE, Madissoon, E. et al. (2022) The discovAIR project: a roadmap towards the Human Lung Cell Atlas. European Respiratory Journal Jan 2022, 2102057; doi: https://doi.org/10.1183/13993003.02057-2021
- HUTER Project. (2022). Data access and DICOM visualization tools (1.0). Zenodo; doi: https://doi.org/10.5281/zenodo.6327116
- HUTER Project. (2022). Data set of ~1 mil scRNAseq for endometrium cells at reproductive age to assess variability among individuals (1.2). Zenodo; doi: https://doi.org/10.5281/zenodo.6327123
- HUTER Project. (2022). Visual system & Digitalisation software (1.0). Zenodo; doi: https://doi.org/10.5281/zenodo.6021818
- HUTER Project. (2021). Methylation Atlas (1.2). Zenodo; doi: https://doi.org/10.5281/zenodo.5795202
- Rozenblatt-Rosen, O, Shin, JW, Rood, JE et al. (2021): Building a high-quality Human Cell Atlas. Nat Biotechnol. 2021 Feb;39(2):149-153; doi: https://doi.org/10.1038/s41587-020-00812-4. PMID: 33500565.
- Sikkema, L, Strobel, D, Zappia, L, et al. (2022). An integrated cell atlas of the human lung in health and disease. bioRxiv 2022.03.10.483747; doi: https://doi.org/10.1101/2022.03.10.483747
- Vilella, F., Wang, W., Moreno, I. et al. (2021). Single-cell RNA sequencing of SARS–CoV-2 cell entry factors in the preconceptional human endometrium. Human Reporduction Vol. 36, Issue 10; doi: https://doi.org/10.1093/humrep/deab183
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